朱佳俊实验室 Zhu Lab

作者 Zhixun Dou · Kanad Ghosh · Maria Grazia Vizioli · Jiajun Zhu · Payel Sen · Kirk J. Wangensteen · Johayra Simithy · Yemin Lan · Yanping Lin · Zhuo Zhou · Brian C. Capell · Caiyue Xu · Mingang Xu · Julia E. Kieckhaefer · Tianying Jiang · Michal Shoshkes-Carmel · K. M. Ahasan Al Tanim · Glen N. Barber · John T. Seykora · Sarah E. Millar · Klaus H. Kaestner · Benjamin A. Garcia · Peter D. Adams · Shelley L Berger

A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription

2016

期刊 G3 Genes|Genomes|Genetics

作者 Morgan A Sammons · Jiajun Zhu · Shelley L Berger

Lysine methylation represses p53 activity in teratocarcinoma cancer cells

2016

期刊 Proceedings of the National Academy of Sciences

作者 Jiajun Zhu · Zhixun Dou · Morgan A Sammons · Arnold J. Levine · Shelley L Berger

MLL1 is essential for the senescence-associated secretory phenotype

2016

期刊 Genes & Development

作者 Brian C. Capell · Adam M. Drake · Jiajun Zhu · Parisha P. Shah · Zhixun Dou · Jean Dorsey · Daniel F. Simola · Greg Donahue · Morgan Sammons · Taranjit Singh Rai · Christopher Natale · Todd W. Ridky · Peter D. Adams · Shelley L Berger

87: Mutant p53 Can Drive Cancer Initiation and Progression Through Gain-of-Function Properties

2015

期刊 American Journal of Clinical Pathology

作者 Apple Long · Jiajun Zhu · Veronique Giroux · Shelley L Berger · Anil K. Rustgi · ...

Autophagy mediates degradation of nuclear lamina

2015

期刊 Nature

作者 Zhixun Dou · Caiyue Xu · Greg Donahue · Takeshi Shimi · Ji-An Pan · Jiajun Zhu · Andrejs Ivanov · Brian C. Capell · Adam M. Drake · Parisha P. Shah · Joseph M. Catanzaro · M. Daniel Ricketts · Trond Lamark · Stephen A. Adam · Ronen Marmorstein · Wei-Xing Zong · Terje Johansen · Robert D. Goldman · Peter D. Adams · Shelley L Berger

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

2015

期刊 Nature

作者 Jiajun Zhu · Morgan A Sammons · Greg Donahue · Zhixun Dou · Masoud Vedadi · Matthäus Getlik · Dalia Barsyte-Lovejoy · Rima Al-Awar · Bryson W. Katona · Ali Shilatifard · Jing Huang · Xianxin Hua · Cheryl H. Arrowsmith · Shelley L Berger

Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2-negative patients with early-onset breast cancer

2014

期刊 Genetics in Medicine

作者 Kara N. Maxwell · Bradley Wubbenhorst · Kurt D’Andrea · Bradley Garman · Jessica M. Long · Jacquelyn Powers · Katherine Rathbun · Jill E. Stopfer · Jiajun Zhu · Angela R. Bradbury · Michael S. Simon · Angela Demichele · Susan M. Domchek · Katherine L. Nathanson

TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity

2014

期刊 Genome Research

作者 Morgan A Sammons · Jiajun Zhu · Adam M. Drake · Shelley L Berger

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Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis

Proline biosynthesis is a vent for TGFβ‐induced mitochondrial redox stress

Metabolic regulation of cell growth and proliferation

Role of Mitochondria in Ferroptosis

Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation

Cytoplasmic chromatin triggers inflammation in senescence and cancer

A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription

Lysine methylation represses p53 activity in teratocarcinoma cancer cells

MLL1 is essential for the senescence-associated secretory phenotype

87: Mutant p53 Can Drive Cancer Initiation and Progression Through Gain-of-Function Properties

Autophagy mediates degradation of nuclear lamina

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2-negative patients with early-onset breast cancer

TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity