Lab of ER Associated Diseases-LEAD 内质网相关疾病实验室

Endoplasmic reticulum associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity

2019

其它

作者 Lu Liu · Ayaka Inoki · Kelly Fan · Fengbiao Mao · Guojun Shi · Xi Jin · Meiling Zhao · Gina Ney · Shengyi Sun · Yali Dou · Ken Inoki · Ling Qi · Qing Li

Hypothalamic ER–associated degradation regulates POMC maturation, feeding, and age-associated obesity

2018

期刊 Journal of Clinical Investigation

作者 Geun Hyang Kim · Guojun Shi · Diane R.m. Somlo · Leena Haataja · Soobin Song · Qiaoming Long · Eduardo A. Nillni · Malcolm J. Low · Peter Arvan · Martin G. Myers · Ling Qi

ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis

2017

期刊 Journal of Clinical Investigation

作者 Guojun Shi · Diane Somlo · Geun Hyang Kim · Cristina Prescianotto-Baschong · Shengyi Sun · Nicole Beuret · Qiaoming Long · Jonas Rutishauser · Peter Arvan · Martin Spiess · Ling Qi

A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death

2015

期刊 Cell Reports

作者 Hongming Ma · Ying Dang · Yonggan Wu · Gengxiang Jia · Edgar Anaya · Junli Zhang · Sojan Abraham · Jang-Gi Choi · Guojun Shi · Ling Qi · N. Manjunath · Haoquan Wu

Free fatty acid receptor 2, a candidate target for type 1 diabetes, induces cell apoptosis through ERK signaling

2014

期刊 Journal of Molecular Endocrinology

作者 Guojun Shi · Chen Sun · Weiqiong Gu · Minglan Yang · Xiaofang Zhang · Nan Zhai · Yan Lu · Zhijian Zhang · Peishun Shou · Zhiguo Zhang · Guang Ning

Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival

2014

期刊 Proceedings of the National Academy of Sciences

作者 Shengyi Sun · Guojun Shi · Xuemei Han · Adam B. Francisco · Yewei Ji · Nuno Mendonça · Xiaojing Liu · Jason W. Locasale · Kenneth W. Simpson · Gerald E. Duhamel · Sander Kersten · John R. Yates · Qiaoming Long · Ling Qi

TAB2, an important upstream adaptor of interleukin-1 signaling pathway, is subject to SUMOylation

2013

期刊 Molecular and Cellular Biochemistry

作者 Xiaolin Wang · Jingjing Jiang · Yan Lu · Guojun Shi · Ruixin Liu · Yanan Cao

Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice

2013

期刊 Gut

作者 Yan Lu · Zhimin Ma · Zhijian Zhang · Xuelian Xiong · Xiaolin Wang · Huijie Zhang · Guojun Shi · Xuefeng Xia · Guang Ning · Xiaoying Li

Caenorhabditis elegans mom-4 is required for the activation of the p38 MAPK signaling pathway in the response to Pseudomonas aeruginosa infection

2012

期刊 Protein & Cell

作者 Ajing Xu · Guojun Shi · Feng Liu · Baoxue Ge

Glucocorticoids Promote Hepatic Cholestasis in Mice by Inhibiting the Transcriptional Activity of the Farnesoid X Receptor

2012

期刊 Gastroenterology

作者 Yan Lu · Zhijian Zhang · Xuelian Xiong · Xiaolin Wang · Jin Li · Guojun Shi · Jian Yang · Xianfeng Zhang · Huijie Zhang · Jie Hong · Xuefeng Xia · Guang Ning · Xiaoying Li

Inhibitory effect of Andrographolide in 3T3-L1 adipocytes differentiation through the PPARγ pathway

2012

期刊 Molecular and Cellular Endocrinology

作者 Lina Jin · Wenqiang Fang · Bo Li · Guojun Shi · Xiaoying Li · Ying Yang · Jian Yang · Zhiguo Zhang · Guang Ning

Andrographolide attenuates tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes

2011

期刊 Molecular and Cellular Endocrinology

作者 Lina Jin · Guojun Shi · Guang Ning · Xiaoying Li · Zhiguo Zhang

Protective effect of andrographolide against concanavalin A-induced liver injury

2011

期刊 Naunyn-Schmiedeberg's Archives of Pharmacology

作者 Guojun Shi · Zhijian Zhang · Rong Zhang · Xiaofang Zhang · Yan Lu · Jian Yang · Di Zhang · Zhiguo Zhang · Xiaoying Li · Guang Ning

Selection of reference genes for quantitative real-time reverse transcription-polymerase chain reaction in concanavalin A-induced hepatitis model

2010

期刊 Analytical Biochemistry

作者 Guojun Shi · Zhijian Zhang · Dechun Feng · Yan Xu · Yan Lu · Jiqiu Wang · Jingjing Jiang · Zhiguo Zhang · Xiaoying Li · Guang Ning

An Essential Role for RIG-I in Toll-like Receptor-Stimulated Phagocytosis

2009

期刊 Cell Host & Microbe

作者 Ling Kong · Lei Sun · Hongxin Zhang · Qin Liu · Ye Liu · Linhua Qin · Guojun Shi · Jun-Hao Hu · Ajing Xu · Yue-Ping Sun · Dangsheng Li · Yu-Fang Shi · Jing-Wu Zang · Jiang Zhu · Zhu Chen · Zhu-Gang Wang · Bao-Xue Ge

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Endoplasmic reticulum associated degradation preserves hematopoietic stem cell quiescence and self-renewal by restricting mTOR activity

Hypothalamic ER–associated degradation regulates POMC maturation, feeding, and age-associated obesity

ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis

A CRISPR-Based Screen Identifies Genes Essential for West-Nile-Virus-Induced Cell Death

Free fatty acid receptor 2, a candidate target for type 1 diabetes, induces cell apoptosis through ERK signaling

Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival

TAB2, an important upstream adaptor of interleukin-1 signaling pathway, is subject to SUMOylation

Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice

Caenorhabditis elegans mom-4 is required for the activation of the p38 MAPK signaling pathway in the response to Pseudomonas aeruginosa infection

Glucocorticoids Promote Hepatic Cholestasis in Mice by Inhibiting the Transcriptional Activity of the Farnesoid X Receptor

Inhibitory effect of Andrographolide in 3T3-L1 adipocytes differentiation through the PPARγ pathway

Andrographolide attenuates tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes

Protective effect of andrographolide against concanavalin A-induced liver injury

Selection of reference genes for quantitative real-time reverse transcription-polymerase chain reaction in concanavalin A-induced hepatitis model

An Essential Role for RIG-I in Toll-like Receptor-Stimulated Phagocytosis