金属蛋白设计研究组

Expansion of Redox Chemistry in Designer Metalloenzymes

2019

期刊 Accounts of Chemical Research

作者 Yang Yu · Xiaohong Liu · Jiangyun Wang

基于肌红蛋白的氧激活蛋白的理性设计

2019

期刊生物加工过程

作者于洋

A genetically engineered Escherichia coli that senses and degrades tetracycline antibiotic residue

2018

期刊 Synthetic and Systems Biotechnology

作者 Zepeng Mu · Zhuoning Zou · Ye Yang · Wenbo Wang · Yue Xu · Jianyi Huang · Ruiling Cai · Ye Liu · Yajin Mo · Boyi Wang · Yiqun Dang · Yongming Li · Yushan Liu · Yueren Jiang · Qingyang Tan · Xiaohong Liu · Cheng Hu · Hua Li · Sha Wei · Chunbo Lou · Yang Yu · Jiangyun Wang

Artificial Metalloenzyme Design with Unnatural Amino Acids and Non-Native Cofactors

2018

期刊 ACS Catalysis

作者 Yang Yu · Cheng Hu · Lin Xia · Jiangyun Wang

Engineering the metal-binding loop at a type 1 copper center by circular permutation

2017

期刊 RSC Advances

作者 Honghui Chen · Binbin Su · Tongtong Zhang · Aiping Huang · Haiping Liu · Yang Yu · Jiangyun Wang

Improving artificial metalloenzymes' activity by optimizing electron transfer

2017

期刊 Chemical Communications

作者 Cheng Hu · Yang Yu · Jiangyun Wang

Biosynthetic approach to modeling and understanding metalloproteins using unnatural amino acids

2016

期刊 Science China Chemistry

作者 Yang Yu · Chang Cui · Jiangyun Wang · Yi Lu

Effect of circular permutation on the structure and function of type 1 blue copper center in azurin

2016

期刊 Protein Science

作者 Yang Yu · Igor D. Petrik · Kelly N. Chacón · Parisa Hosseinzadeh · Honghui Chen · Ninian J. Blackburn · Yi Lu

A Designed Metalloenzyme Achieving the Catalytic Rate of a Native Enzyme

2015

期刊 Journal of the American Chemical Society

作者 Yang Yu · Chang Cui · Xiaohong Liu · Igor D. Petrik · Jiangyun Wang · Yi Lu

Defining the Role of Tyrosine and Rational Tuning of Oxidase Activity by Genetic Incorporation of Unnatural Tyrosine Analogs

2015

期刊 Journal of the American Chemical Society

作者 Yang Yu · Xiaoxuan Lv · Jiasong Li · Qing Zhou · Chang Cui · Parisa Hosseinzadeh · Arnab Mukherjee · Mark J. Nilges · Jiangyun Wang · Yi Lu

Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid

2015

期刊 Chemical Science

作者 Yang Yu · Qing Zhou · Li Wang · Xiaohong Liu · Wei Zhang · Meirong Hu · Jianshu Dong · Jiasong Li · Xiaoxuan Lv · Hanlin Ouyang · Han Li · Feng Gao · Weimin Gong · Yi Lu · Jiangyun Wang

Ultrafast Photoinduced Electron Transfer in Green Fluorescent Protein Bearing a Genetically Encoded Electron Acceptor

2015

期刊 Journal of the American Chemical Society

作者 Xiaoxuan Lv · Yang Yu · Meng Zhou · Cheng Hu · Feng Gao · Jiasong Li · Xiaohong Liu · Kai Deng · Peng Zheng · Weimin Gong · Andong Xia · Jiangyun Wang

Direct EPR Observation of a Tyrosyl Radical in a Functional Oxidase Model in Myoglobin during both H2O2and O2Reactions

2014

期刊 Journal of the American Chemical Society

作者 Yang Yu · Arnab Mukherjee · Mark J. Nilges · Parisa Hosseinzadeh · Kyle D. Miner · Yi Lu

Metalloproteins Containing Cytochrome, Iron–Sulfur, or Copper Redox Centers

2014

期刊 Chemical Reviews

作者 Jing Liu · Saumen Chakraborty · Parisa Hosseinzadeh · Yang Yu · Shiliang Tian · Igor Petrik · Ambika Bhagi · Yi Lu

Significant Enhancement of hPrx1 Chaperone Activity through Lysine Acetylation

2014

期刊 ChemBioChem

作者 Yanchao Pan · Jing-Hua Jin · Yang Yu · Jiangyun Wang

Significant Increase of Oxidase Activity through the Genetic Incorporation of a Tyrosine-Histidine Cross-Link in a Myoglobin Model of Heme-Copper Oxidase

2012

期刊 Angewandte Chemie

作者 Xiaohong Liu · Yang Yu · Cheng Hu · Wei Zhang · Yi Lu · Jiangyun Wang

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Expansion of Redox Chemistry in Designer Metalloenzymes

基于肌红蛋白的氧激活蛋白的理性设计

A genetically engineered Escherichia coli that senses and degrades tetracycline antibiotic residue

Artificial Metalloenzyme Design with Unnatural Amino Acids and Non-Native Cofactors

Engineering the metal-binding loop at a type 1 copper center by circular permutation

Improving artificial metalloenzymes' activity by optimizing electron transfer

Biosynthetic approach to modeling and understanding metalloproteins using unnatural amino acids

Effect of circular permutation on the structure and function of type 1 blue copper center in azurin

A Designed Metalloenzyme Achieving the Catalytic Rate of a Native Enzyme

Defining the Role of Tyrosine and Rational Tuning of Oxidase Activity by Genetic Incorporation of Unnatural Tyrosine Analogs

Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid

Ultrafast Photoinduced Electron Transfer in Green Fluorescent Protein Bearing a Genetically Encoded Electron Acceptor

Direct EPR Observation of a Tyrosyl Radical in a Functional Oxidase Model in Myoglobin during both H2O2and O2Reactions

Metalloproteins Containing Cytochrome, Iron–Sulfur, or Copper Redox Centers

Significant Enhancement of hPrx1 Chaperone Activity through Lysine Acetylation

Significant Increase of Oxidase Activity through the Genetic Incorporation of a Tyrosine-Histidine Cross-Link in a Myoglobin Model of Heme-Copper Oxidase