系统与进化基因组学实验室

Distinct codon usage bias evolutionary patterns between weakly and strongly virulent respiratory viruses

2021

期刊 iScience 有全文

作者 Feng Chen · Jian-Rong Yang

Expression level is a major modifier of the fitness landscape of a protein coding gene

2021

期刊 Nature Ecology & Evolution

作者 Zhuoxing Wu · Xiujuan Cai · Xin Zhang

Specificity of RNA Folding and Its Association with Evolutionarily Adaptive mRNA Secondary Structures

2021

期刊 Genomics Proteomics & Bioinformatics

作者 Gongwang Yu · Hanbing Zhu · Xiaoshu Chen · Jian-Rong Yang

Alignment of Cell Lineage Trees Elucidates Genetic Programs for the Development and Evolution of Cell Types

2020

期刊 iScience

作者 Meng Yuan · Xujiang Yang · Jinghua Lin · Xiaolong Cao · Feng Chen · Xiaoyu Zhang · Zizhang Li · Guifeng Zheng · Xueqin Wang · Xiaoshu Chen · Jian-Rong Yang

Bidirectional genetic control of phenotypic heterogeneity and its implication for cancer drug resistance

2020

期刊 Molecular Biology and Evolution 有全文

作者 Ning Mo · Xiaoyu Zhang · Wenjun Shi · Gongwang Yu · Xiaoshu Chen · Jian-Rong Yang

Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection

2020

期刊 Nature Ecology & Evolution

作者 Feng Chen · Peng Wu · Shuyun Deng · Heng Zhang · Yutong Hou · Zheng Hu · Jianzhi Zhang · Xiaoshu Chen · Jian-Rong Yang

Genomic variations of COVID-19 suggest multiple outbreak sources of transmission

2020

期刊 medRxiv 有全文

作者 Liangsheng Zhang · Jian-Rong Yang · Zhenguo Zhang · Zhenguo Lin

In vitro and in vivo growth inhibition of human cervical cancer cells via human papillomavirus E6/E7 mRNAs’ cleavage by CRISPR/Cas13a system

2020

期刊 Antiviral Research

作者 Yili Chen · Hongye Jiang · Ting Wang · Dan He · Rui Tian · Zifeng Cui · Xun Tian · Qinglei Gao · Xin Ma · Jianrong Yang · Jun Wu · Songwei Tan · Hongyan Xu · Xiongzhi Tang · Yan Wang · Zhiying Yu · Hui Han · Bhudev C Das · Konstantin Severinov · Inga Isabel Hitzeroth · Priya Ranjan Debata · Wei Xu · Weiwen Fan · Zhuang Jin · Chen Cao · Miao Yu · Weiling Xie · Zhaoyue Huang · Zheng Hu · Zeshan You

The Evolution of Sex Chromosome Dosage Compensation in Animals

2020

期刊 Journal of Genetics and Genomics

作者 Jiabi Chen · Menghan Wang · Xionglei He · Jian-Rong Yang · Xiaoshu Chen

Transcriptome Analysis in Yeast Reveals the Externality of Position Effect

2020

期刊 bioRxiv 有全文

作者 Qian Gui · Shuyun Deng · Wenjun Shi · Xiujuan Cai · Zhen-Zhen Zhou · Jian-Rong Yang · Xiaoshu Chen

Computational comparison of developmental cell lineage trees by alignments

2019

期刊 bioRxiv

作者 Meng Yuan · Xujiang Yang · Jinghua Lin · Xiaolong Cao · Feng Chen · Xiaoyu Zhang · Zizhang Li · Guifeng Zheng · Xueqin Wang · Xiaoshu Chen · Jian-Rong Yang

Risk stratification of cervical lesions using capture sequencing and machine learning method based on HPV and human integrated genomic profiles

2019

期刊 Carcinogenesis

作者 Rui Tian · Zifeng Cui · Dan He · Xun Tian · Qinglei Gao · Xin Ma · Jian-Rong Yang · Jun Wu · Bhudev C Das · Konstantin Severinov · Inga Isabel Hitzeroth · Priya Ranjan Debata · Wei Xu · Haolin Zhong · Weiwen Fan · Yili Chen · Zhuang Jin · Chen Cao · Miao Yu · Weiling Xie · Zhaoyue Huang · Yuxian Bao · Hongxian Xie · Shuzhong Yao · Zheng Hu

The expression tractability of biological traits shaped by natural selection

2019

期刊 Journal of Genetics and Genomics

作者 Li Liu · Jianguo Wang · Jian-Rong Yang · Feng Wang · Xionglei He

Dosage sensitivity of X-linked genes in human embryonic single cells

2018

期刊 BMC Genomics

作者 Xiaoshu Chen · Jian-Rong Yang

The expression tractability of a biological trait

2018

期刊 bioRxiv 有全文

作者 Li Liu · Jianguo Wang · Jianrong Yang · Xionglei He

Deciphering the Genic Basis of Yeast Fitness Variation by Simultaneous Forward and Reverse Genetics

2017

期刊 Molecular Biology and Evolution

作者 Calum J. Maclean · Brian P.h. Metzger · Jian-Rong Yang · Wei-Chin Ho · Bryan Moyers · Jianzhi Zhang

Does mRNA structure contain genetic information for regulating co-translational protein folding?

2017

期刊 Zoological Research

作者 Jian-Rong Yang

Intra and Interspecific Variations of Gene Expression Levels in Yeast Are Largely Neutral: (Nei Lecture, SMBE 2016, Gold Coast)

2017

期刊 Molecular Biology and Evolution

作者 Jian-Rong Yang · Calum J. Maclean · Chungoo Park · Huabin Zhao · Jianzhi Zhang

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Distinct codon usage bias evolutionary patterns between weakly and strongly virulent respiratory viruses

Expression level is a major modifier of the fitness landscape of a protein coding gene

Specificity of RNA Folding and Its Association with Evolutionarily Adaptive mRNA Secondary Structures

Alignment of Cell Lineage Trees Elucidates Genetic Programs for the Development and Evolution of Cell Types

Bidirectional genetic control of phenotypic heterogeneity and its implication for cancer drug resistance

Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection

Genomic variations of COVID-19 suggest multiple outbreak sources of transmission

In vitro and in vivo growth inhibition of human cervical cancer cells via human papillomavirus E6/E7 mRNAs’ cleavage by CRISPR/Cas13a system

The Evolution of Sex Chromosome Dosage Compensation in Animals

Transcriptome Analysis in Yeast Reveals the Externality of Position Effect

Computational comparison of developmental cell lineage trees by alignments

Risk stratification of cervical lesions using capture sequencing and machine learning method based on HPV and human integrated genomic profiles

The expression tractability of biological traits shaped by natural selection

Dosage sensitivity of X-linked genes in human embryonic single cells

The expression tractability of a biological trait

Deciphering the Genic Basis of Yeast Fitness Variation by Simultaneous Forward and Reverse Genetics

Does mRNA structure contain genetic information for regulating co-translational protein folding?

Intra and Interspecific Variations of Gene Expression Levels in Yeast Are Largely Neutral: (Nei Lecture, SMBE 2016, Gold Coast)