实验室简介
实验室简介
生命活动的本质是具有一定随机性的生化反应，由此产生的随机现象可以通过各种方式影响生物的功能与进化，并与人类健康具有深入的联系。我们从进化基因组与系统生物学的角度，分析生物活动各个层面的随机现象，并发展相关的研究方法和分析工具。
Genetic regulation of phenotypic heterogeneity
Isogenic cells could have vastly different phenotypes. Such phenotypic heterogeneity is stochastic in its nature, but is also highly regulated. Phenotypic heterogeneity ensures poulation survival in the face of extreme environments, but is also deleterious as it lowere the population-average fitness by driving some individuals away from the phenotypic optimum. It has also been implicated in antibiotic resistance bacteria or chemo-resistance of cancer cells. We aimed to identify...
